Gene name:
Apba1 (Mint1;X11) ;
Protein name:
Amyloid beta A4 precursor protein-binding family A member 1 ;
Alternative:
Neuron-specific X11 protein ;Adapter protein X11alpha ;Neuronal Munc18-1-interacting protein 1 (Mint-1) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Part of a multimeric complex containing Munc18-1 and syntaxin-1. Also part of the brain-specific heterotrimeric complex LIN-10/X11-alpha, LIN-2/CASK, and LIN7. Binds to the cytoplasmic domain of amyloid protein (APP).
Function:
Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-AAP.
Subcellular Location:
N/A
Protein Attributes:
50:
MNHLEGSAEV | EVADEAPGGE | VNESVEADLE | HPEVEEEQQP | SPPPPAGHAP |
100:
EDHRAHPAPP | PPPPPQEEEE | ERGECLARSA | STESGFHNHT | DTAEGDVLAA |
150:
ARDGYEAERA | QDADDESAYA | VQYRPEAEEY | TEQAEAEHAE | AAQRRALPNH |
200:
LHFHSLEHEE | AMNAAYSGYV | YTHRLFHRAE | DEPYAEPYAD | YGGLQEHVYE |
250:
EIGDAPELEA | RDGLRLYERE | RDEAAAYRQE | ALGARLHHYD | ERSDGESDSP |
300:
EKEAEFAPYP | RMDSYEQEED | IDQIVAEVKQ | SMSSQSLDKA | AEDMPEAEQD |
350:
LERAPTPGGG | HPDSPGLPAP | AGQQQRVVGT | PGGSEVGQRY | SKEKRDAISL |
400:
AIKDIKEAIE | EVKTRTIRSP | YTPDEPKEPI | WVMRQDISPT | RDCDDQRPVD |
450:
GDSPSPGSSS | PLGAESSITP | LHPGDPTEAS | TNKESRKSLA | SFPTYVEVPG |
500:
PCDPEDLIDG | IIFAANYLGS | TQLLSDKTPS | KNVRMMQAQE | AVSRIKTAQK |
550:
LAKSRKKAPE | GESQPMTEVD | LFISTQRIKV | LNADTQEPMM | DHPLRTISYI |
600:
ADIGNIVVLM | ARRRMPRSNS | QENVEASHPS | QDAKRQYKMI | CHVFESEDAQ |
650:
LIAQSIGQAF | SVAYQEFLRA | NGINPEDLSQ | KEYSDLLNTQ | DMYNDDLIHF |
700:
SKSENCKDVF | IEKQKGEILG | VVIVESGWGS | ILPTVIIANM | MHGGPAEKSG |
750:
KLNIGDQIMS | INGTSLVGLP | LSTCQSIIKG | LKNQSRVKLN | IVRCPPVTTV |
800:
LIRRPDLRYQ | LGFSVQNGII | CSLMRGGIAE | RGGVRVGHRI | IEINGQSVVA |
839:
TPHEKIVHIL | SNAVGEIHMK | TMPAAMYRLL | TAQEQPVYI
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
ELISA Kit for Rat Amyloid beta A4 precursor protein-binding family A member 1
ELISA Kit for Rat Amyloid beta A4 precursor protein-binding family A member 1
ELISA Kit for Rat Amyloid beta A4 precursor protein-binding family A member 1
CLIA Kit for Rat Amyloid beta A4 precursor protein-binding family A member 1
CLIA Kit for Rat Amyloid beta A4 precursor protein-binding family A member 1
CLIA Kit for Rat Amyloid beta A4 precursor protein-binding family A member 1
Polyclonal Antibody for Rat Amyloid beta A4 precursor protein-binding family A member 1
Polyclonal Antibody for Rat Amyloid beta A4 precursor protein-binding family A member 1
Polyclonal Antibody for Rat Amyloid beta A4 precursor protein-binding family A member 1
Monoclonal Antibody for Rat Amyloid beta A4 precursor protein-binding family A member 1
Monoclonal Antibody for Rat Amyloid beta A4 precursor protein-binding family A member 1
Monoclonal Antibody for Rat Amyloid beta A4 precursor protein-binding family A member 1
Protein for Rat Amyloid beta A4 precursor protein-binding family A member 1
Protein for Rat Amyloid beta A4 precursor protein-binding family A member 1
Protein for Rat Amyloid beta A4 precursor protein-binding family A member 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH CASK AND LIN7
tissue :
Testis .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;INTERACTION WITH FSBP
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 453-643;AUTOINHIBITORY DOMAIN;MUTAGENESIS OF TYR-633;INTERACTION WITH APP